Biologic for allergic asthma

Omalizumab (Xolair) is sometimes used to treat asthma triggered by airborne allergens. If you have allergies, your immune system identifies a harmless airborne substance — such as pollen, dust mites and pet dander — as being harmful. This substance is called an allergen.

Your immune system is how your body protects itself, so it produces immunoglobulin E (IgE) antibodies to protect against this allergen. These antibodies signal your immune system to release chemicals into your bloodstream, causing a reaction that leads to allergy and asthma symptoms. Omalizumab blocks the action of these antibodies, reducing the immune system reaction.

Omalizumab is given as an injection every 2 to 4 weeks. It isn't generally recommended for children under 12 years of age. In rare cases, this medication has triggered a life-threatening allergic reaction (anaphylaxis). In addition, the U.S. Food and Drug Administration (FDA) has issued a warning about a slightly increased risk of heart and brain blood vessel problems while taking this drug.

Anyone who gets an injection of this drug should be monitored closely by health care professionals in case of a severe reaction.