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At-home colon cancer tests

Multitarget stool DNA test

A multitarget stool DNA test (mt-sDNA) finds tiny amounts of hemoglobin and cells in your stool. The test checks for changes in the cells' genetic material, which also is called DNA. Certain DNA changes are a sign that cancer is present or that it might happen in the future.

A stool DNA test (Cologuard) checks for bleeding from the lower digestive tract. This test is recommended every three years.

How you take the test:

  • You don't need to prepare. You can eat, drink and take your medicines as usual before you collect a stool sample.
  • This test is only available with a prescription. You receive the kit in the mail.
  • The kit includes a container that attaches to the toilet. The kit also contains a preservative solution that you add to the stool sample before sealing the container.
  • You collect one entire bowel movement in the container.
  • After you collect the stool sample, return the sealed container to your healthcare professional's office or ship it to the lab. Return it within 24 hours.