Risks

Aromatase inhibitors increase the risk of osteoporosis and may affect the heart.

Unlike tamoxifen and raloxifene, aromatase inhibitors do not raise the risk of blood clots or uterine cancer. Because aromatase inhibitors are a newer type of medicine, more research is needed to understand long-term health risks, such as heart conditions and bone loss.

As more is learned through research studies, healthcare professionals will better understand the long-term health effects of these medicines and how well they work to prevent breast cancer.