Fatigue

Feeling tired and run-down is the most common side effect of both interferon-based and interferon-free treatments. To avoid fatigue or limit its impact, try:

• Scheduling interferon injections for days when you can take it easy — at the start of a weekend, for example
• Cutting back on work hours, if possible
• Napping during the day
• Taking a walk on most days to increase your alertness and promote better sleep
• Drinking a caffeinated beverage in the morning
• Considering antidepressant therapy if depression may be contributing to your fatigue