Safety and side effects

When taken by mouth at recommended doses, creatine is likely safe for many people to take for up to five years. As with any dietary supplement, it's important to choose a product that follows recommended manufacturing practices and uses third-party testing to make sure the product is high quality.

Creatine can cause side effects such as:

• Weight gain.

Research on creatine use in people with kidney disease is limited. People with kidney disease may want to talk with their healthcare teams before using creatine.