Mayo Clinic Care Network Content
Articles

Different types of COVID-19 vaccines: How they work

Protein subunit vaccine

Subunit vaccines include only the parts of a virus that best stimulate the immune system. This type of COVID-19 vaccine has harmless S proteins in it. Once the immune system recognizes the S proteins, it creates antibodies and defensive white blood cells. If infection with the COVID-19 virus happens later, the antibodies help clear out the virus.

The Novavax COVID-19 vaccine is a protein subunit vaccine.