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Genetic testing for breast cancer: Psychological and social impact

Negative test results

Learning that genetic testing found no gene changes linked to an increased risk of breast cancer can bring a range of emotions. These include:

  • Relief about your results. You may feel a strong sense of relief if your test result is negative for gene changes linked to breast cancer that have been found in other family members. You also may feel relief if testing does not find a hereditary gene change despite a strong family history of breast cancer. But given your family history, you should work with your healthcare professional to make a screening plan based on your particular situation.

    It is important not to let a negative test result create a false sense of security. You still face the same risk of cancer as the general population or a slightly higher risk based on your family history.

  • Survivor guilt. Testing negative for gene changes linked to a higher risk of breast cancer can cause feelings of guilt. This is especially true if other family members do carry the gene changes and face an increased cancer risk.
  • Uncertainty about your cancer risk. A negative test result doesn't mean you have no risk of cancer. It may be difficult for your healthcare professionals to find your precise level of risk.