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HER2-negative breast cancer: Understanding your diagnosis

HR-positive/HER2-negative breast cancer

The HER2-negative subtype HR-positive/HER2-negative breast cancer is typically treated with surgery if the cancer is in its early stages. Medicines called estrogen blockers also are usually given to lower the chance of the cancer coming back. If cancer comes back, that is called a recurrence.

If HR-positive/HER2-negative cancer spreads to distant parts of the body, treatment usually focuses on slowing the growth of the cancer and managing symptoms. Treatment often starts with chemotherapy or other medicines.