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How vaccines actually work: A simple guide

Live vaccines

Live vaccines use a weakened form of a germ to help your body build protection without making you sick. Live vaccines protect against:

  • Chickenpox, also called varicella.
  • Measles, mumps and rubella (MMR).
  • Rotavirus.
  • Smallpox.
  • Yellow fever.

Live vaccines are usually given to people who have healthy immune systems. They aren't recommended for people who have weakened immune systems, like those getting chemotherapy.