Pain relievers

Some common pain relievers can harm the liver.

Nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Motrin) and naproxen sodium (Aleve) can damage the liver, especially when used often or with alcohol. These medicines should usually be avoided by people with liver disease or those who have had a liver transplant.

Acetaminophen (Tylenol) is considered safe at proper doses. But it is very dangerous in overdose. In fact, overdose is the most common cause of acute liver failure. Acetaminophen is in more than 600 medicines, so always check labels for "acetaminophen," "acetam" or "APAP."

For people with chronic liver disease, less than 2 grams a day, in divided doses, is generally considered safe. Always ask your healthcare team before taking any amount. Acetaminophen is generally safer than an NSAID for people with liver disease when used correctly.