What to know about medication side effects

All medicines — including those used to manage liver failure — can cause side effects. Many side effects are mild and improve with time. Others may require changing the dose or switching to a different medicine.

Here are examples of possible side effects connected to medicines used in liver failure or after liver transplant:

• Corticosteroids. These medications may be used as antirejection medicines after transplant. Common side effects include increased appetite, weight gain, high blood sugar, high blood pressure and roundness of the face, referred to as moon face. Other common side effects include bone thinning, called osteoporosis, and sleep problems.
• Immunosuppressants. These medications are used for antirejection after liver transplant. The side effects of immunosuppressants vary depending on the amount and kind taken. Some common side effects include diabetes, high blood pressure, high cholesterol, increased risk of infection and stomach issues.
• Diuretics. Diuretics are used to manage fluid buildup in liver failure. Side effects depend on the amount and kind taken. Generally, common side effects may include dehydration, headache, frequent urination, a change in potassium or sodium levels, skin reactions, stomach issues, restlessness, and fatigue.

While side effects can be uncomfortable, many can be prevented or managed. Never stop or change any medicines on your own. If a side effect becomes hard to manage or affects your daily life, tell your healthcare team. Your care team can help balance treatment effectiveness with safety and comfort.

And talk with your healthcare team about every medicine you take — including medications available without a prescription and supplements. Your care team can help you understand the possible side effects and manage them. Your healthcare professional can adjust your overall treatment plan if needed.