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Monoamine oxidase inhibitors (MAOIs)

Side effects of MAOIs

MAOIs most often are tried when other antidepressants don't help.

The most common side effects of MAOIs include:

  • Dry mouth.
  • Upset stomach.
  • Diarrhea or constipation.
  • Headache.
  • Sleepiness during the day.
  • Trouble sleeping at night.
  • Dizziness or lightheadedness.
  • Skin irritation at the patch site.

Less common side effects include:

  • Muscle cramps or jerks.
  • Low blood pressure.
  • Less sexual desire or trouble reaching orgasm.
  • Weight gain.
  • Trouble starting a urine flow.
  • Prickling or tingling feeling in the skin.