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Prednisone and other corticosteroids

Side effects of corticosteroid shots

Corticosteroid shots can cause short-term side effects near the site of the shot. These effects may include skin thinning or loss of color in the skin. Rarely, shots into joints may make joint pain and swelling worse for a few days. This pain is known as postinjection flare.

Other symptoms may include facial flushing, not being able to sleep and high blood sugar. Healthcare professionals most often limit corticosteroid injections to 3 to 4 a year.