Antidepressants with a sedating effect

Sometimes prescription medicines used mainly to treat depression may ease insomnia when taken in lower doses. Although widely used, these are not approved by the U.S. Food and Drug Administration (FDA) for insomnia. When insomnia is related to depression or anxiety, these antidepressants may be added to treatment.

Examples include:

• Amitriptyline
• Mirtazapine (Remeron)
• Trazodone