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Prescription weight-loss drugs

Bupropion-naltrexone (Contrave)

Bupropion-naltrexone is a mix of two medicines. Naltrexone treats alcohol and opioid overuse. Bupropion treats depression and helps people stop smoking. When combined into one pill, this medicine helps people lose weight. You take it by mouth once or twice a day.

Bupropion-naltrexone can raise blood pressure. So your healthcare professional needs to check your blood pressure regularly at the start of treatment. Common side effects include upset stomach, headache and trouble passing stool. The medicine also may cause depression, changes in thinking and suicidal thoughts.