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Prescription weight-loss drugs

Other weight-loss drugs

The FDA also has approved setmelanotide (Imcivree). But it's only for people age 6 and older who have obesity due to one of these rare conditions that are passed through families, called inherited:

  • Proopiomelanocortin deficiency.
  • Proprotein subtilisin-kexin type 1 deficiency.
  • Leptin receptor deficiency.
  • Bardet-Biedl syndrome.

Setmelanotide doesn't treat any of the gene issues that cause these conditions. But taken as a daily shot, it can help people with one of these conditions lose weight. It can make them want to eat less and make them feel full sooner. And it may help them burn more calories.

Side effects include headache, skin darkening, upset stomach, loose stools, belly pain, depression and thoughts of suicide.