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Prescription weight-loss drugs

Phentermine-topiramate (Qsymia)

Phentermine-topiramate is a mix of the weight-loss drug phentermine and the anticonvulsant topiramate. You take it by mouth once a day.

Phentermine is a Schedule IV drug. This is a label given to drugs that have a risk of misuse. But the rate of misuse seems to be low.

Side effects may include a faster heart rate and higher blood pressure, not being able to sleep, trouble passing stool, and being nervous. Topiramate raises the risk of birth defects.

Phentermine by itself (Adipex-P, Lomaira) is another weight-loss medicine. It's one of four weight-loss drugs the FDA approved for use for short-term use. Short-term use is less than 12 months.