Articles
Serotonin and norepinephrine reuptake inhibitors (SNRIs)
Safety issues
Content
How SNRIs work
SNRIs approved to treat depression
Side effects and cautions
Safety issues with SNRIs
Suicide risk and antidepressants
Stopping treatment with SNRIs
Finding the right antidepressant
Content
How SNRIs work
SNRIs approved to treat depression
Side effects and cautions
Safety issues with SNRIs
Suicide risk and antidepressants
Stopping treatment with SNRIs
Finding the right antidepressant
How SNRIs work
SNRIs ease depression by affecting chemical messengers called neurotransmitters that affect mood.
SNRIs block the reabsorption, also called reuptake, of the neurotransmitters serotonin (ser-o-TOE-nin) and norepinephrine (nor-ep-ih-NEF-rin) in the brain. Blocking reabsorption makes more of these chemicals available to help ease depression symptoms.