Liver damage

Sometimes, statin use could cause an increase in the level of enzymes in the liver. These enzymes signal inflammation. If the increase is only mild, you can continue to take the statin. Rarely, if the increase is severe, you may need to try a different statin.

Although liver problems are rare, your healthcare team may order a liver enzyme test before or shortly after you begin to take a statin. You won't need any further liver enzyme tests unless you begin to have signs of trouble with your liver.

Contact your healthcare professional right away if you have unusual fatigue or weakness, loss of appetite, pain in your upper stomach, dark-colored urine, or yellowing of your skin or eyes.