Mayo Clinic Care Network Content
Articles

Tianeptine: Is safe use possible?

Content
Side effects and withdrawal symptoms

Side effects and withdrawal symptoms

Tianeptine can have side effects, even when taken at lower doses. These may include:

  • Abdominal pain.
  • Bad dreams.
  • Constipation.
  • Dizziness.
  • Drowsiness.
  • Dry mouth.
  • Headache.
  • Nausea.

When people stop taking tianeptine they may have withdrawal symptoms right away. Symptoms of tianeptine withdrawal are similar to those of opioid withdrawal and may include:

  • Agitation.
  • Anxiety.
  • Chills and trembling.
  • Depression.
  • Muscle pain.
  • Sweating.

While tianeptine may help treat depression, anxiety and irritable bowel syndrome, the risks often outweigh the benefits. Tianeptine is usually sold as a dietary supplement that can help with energy, mood, pain, sexual performance and appetite control. However, tianeptine can have ill effects and can even lead to death. Talk to your healthcare professional if you have questions about care for depression, anxiety or other conditions.