Stopping treatment with tricyclic antidepressants

Tricyclic antidepressants aren't considered habit-forming. But suddenly stopping antidepressant treatment or missing several doses can cause withdrawal-like symptoms. Symptoms may vary depending on how the medicine works. This is sometimes called discontinuation syndrome. Work with your healthcare professional to slowly and safely lower your dose over time.

Withdrawal-like symptoms can include:

• Restlessness, irritability or anxiety.
• Upset stomach.
• Feelings of tingling or burning.
• Flu-like symptoms, such as chills, sweating and muscle aches.
• Trouble sleeping.
• Sluggishness, tiredness or sleepiness.
• Headache.
• Dizziness.