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Vaccine guidance from Mayo Clinic

Meningococcal conjugate (MenACWY)

Meningococcal disease is a rare, severe bacterial infection that can cause permanent disabilities or death. The bacteria that causes the disease can infect the fluid and membrane surrounding the brain or spinal cord, a disease called meningitis. Or it can enter the bloodstream or spark an infection in the joints or heart.

Anyone can get meningococcal disease. Among children, meningococcal disease is more likely to affect infants younger than age 1 and adolescents and young adults ages 16 through 23. It's also more likely to affect children with certain medical conditions that affect the immune system. Young adults living in groups, such as in college or during military training, may be at higher risk than the average person.

The meningococcal conjugate vaccine can help protect against meningococcal disease caused by the bacteria strains A, C, W and Y. This vaccine is given as one shot. It is routinely recommended at age 11 or 12. A booster dose involving one shot is recommended at age 16. This vaccine can also be given to children between the ages of 2 months and 10 years who are at high risk of bacterial meningitis or who have been exposed to someone with the disease.

The meningococcal ACWY vaccine uses inactive parts of the A, C, W and Y bacteria strains. After vaccination, the body begins building an immune response against the bacteria. The meningococcal ACWY vaccine is 80% effective at preventing meningococcal disease one year after vaccination. But protection gradually fades over five years. That's why it's important to give the booster dose at age 16, when the risk of meningococcal disease increases.

This vaccine shouldn't be given to a child who has:

  • A history of an allergic reaction to any previous dose of a meningococcal ACWY vaccine
  • Any severe, life-threatening allergies