Diseases and Conditions

Floor of the mouth cancer

Overview

Floor of the mouth cancer is cancer that begins on the tissue underneath your tongue.

Floor of the mouth cancer most often begins in the thin, flat cells that line the inside of your mouth (squamous cells). Changes in the look and feel of the tissue on the floor of the mouth, such as a lump or a sore that doesn't heal, are often the first signs of floor of the mouth cancer.

Floor of the mouth cancer treatments include surgery, radiation therapy and chemotherapy.