Diseases and Conditions

Histoplasmosis

Symptoms

The mildest forms of histoplasmosis cause no signs or symptoms, but severe infections can be life-threatening. When signs and symptoms occur, they usually appear three to 17 days after exposure and can include:

  • Fever
  • Chills
  • Headache
  • Muscle aches
  • Dry cough
  • Chest discomfort
  • Fatigue

Some people with histoplasmosis also get joint pain and a rash. People who have a lung disease, such as emphysema, can develop a chronic form of histoplasmosis.

Signs of chronic histoplasmosis can include weight loss and a bloody cough. The symptoms of chronic histoplasmosis sometimes mimic those of tuberculosis.

Severe histoplasmosis

The most severe variety of histoplasmosis occurs primarily in infants and in people with compromised immune systems. Called disseminated histoplasmosis, it can affect nearly any part of your body, including your mouth, liver, central nervous system, skin and adrenal glands. If untreated, disseminated histoplasmosis is usually fatal.

When to see a doctor

Contact your doctor if you develop flu-like symptoms after being exposed to bird or bat droppings — especially if you have a weakened immune system.