Diseases and Conditions

Lobular carcinoma in situ (LCIS)

Risk factors

Your risk of LCIS may be increased if:

  • You have a family history of breast cancer. If one or more close relatives have been diagnosed with breast cancer, you may have an increased risk of LCIS.
  • You've taken hormone replacement therapy for menopause. Women who have used hormone replacement therapy for more than three to five years to help cope with menopausal signs and symptoms may have an increased risk of LCIS.
  • You're a woman in your early 40s. Though LCIS is uncommon, it's most likely to be detected in women in their early 40s who haven't yet experienced menopause. However, LCIS is becoming more common in older women who have undergone menopause.