Diseases and Conditions

Sjogren's syndrome

Causes

Sjogren's syndrome is an autoimmune disorder. Your immune system mistakenly attacks your body's own cells and tissues.

Scientists aren't certain why some people develop Sjogren's syndrome. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary.

In Sjogren's syndrome, your immune system first targets the glands that make tears and saliva. But it can also damage other parts of your body, such as:

  • Joints
  • Thyroid
  • Kidneys
  • Liver
  • Lungs
  • Skin
  • Nerves