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Alzheimer's: Medicines help manage symptoms and slow decline

FDA-approved medicines for treating symptoms

The Food and Drug Administration (FDA) has approved medicines to treat symptoms at different stages of Alzheimer's disease — mild, moderate and severe. These stages are based on scores on tests that assess memory, awareness of time and place, thinking, and reasoning. Most people with Alzheimer's disease take one or more of these medicines at some time during treatment:

  • Cholinesterase (ko-lin-ES-tur-ays) inhibitors.
  • Memantine.
  • Brexpiprazole.

These medicines aren't approved or recommended for treating mild cognitive impairment (MCI). Symptoms of MCI are small but notable changes in memory and thinking. The most common cause of MCI is Alzheimer's disease. MCI due to Alzheimer's can be a stage between typical age-related memory changes and Alzheimer's disease dementia. Some people with MCI do not have Alzheimer's disease but may have other causes of their condition.

Healthcare professionals might prescribe these Alzheimer's medicines for stages other than the officially approved stage. Alzheimer's stages aren't exact, and individual responses to medicines vary. Also, treatment options are limited.