Mayo Clinic Care Network Content
Articles

Anaphylaxis: First aid

Treatment

After you call 911 or your local medical emergency number, do the following:

  • Ask if the person is carrying an epinephrine autoinjector (EpiPen, Auvi-Q, others) to treat an allergic attack.
  • If the person needs to use an autoinjector, ask whether you should help inject the medicine. This most often is done by pressing the autoinjector against the person's thigh.
  • Have the person lie face up and be still.
  • Loosen tight clothing and cover the person with a blanket.
  • If there's vomiting or bleeding from the mouth, turn the person to the side to prevent choking.
  • If there are no signs of breathing, coughing or movement, begin CPR. Keep doing about 100 chest presses every minute until paramedics arrive.

An antihistamine pill, such as diphenhydramine (Benadryl), isn't enough to treat anaphylaxis. These medicines can help relieve allergy symptoms, but they work too slowly in a severe reaction.