Onabotulinumtoxin type A (Botox)

How it works

Injections of Botox into the bladder muscle might benefit people who have an overactive bladder or urge incontinence. Botox blocks the actions of acetylcholine, which makes you have fewer involuntary bladder contractions. This can ease urinary urgency and other urge incontinence symptoms.

Botox might be helpful for people who haven't responded to other medicines. Benefits can last several months. Your healthcare professional might recommend repeating the injections once or twice a year.

Side effects

Studies have found that Botox significantly improves symptoms of incontinence. Side effects include urinary retention, which happens when the bladder doesn't fully empty during urination. Some research also shows it may increase urinary tract infections.

The Food and Drug Administration (FDA) warns that adverse reactions may occur after the use of Botox for both approved and unapproved use. They can include stopping breathing and death.