Who they're for

Aromatase inhibitors are effective in treating breast cancer and preventing its return after menopause. Aromatase inhibitors are not used to prevent breast cancer from returning if you still have menstrual cycles.

Studies have looked into whether certain aromatase inhibitors, such as exemestane and anastrozole, can reduce the risk of breast cancer in people at high risk. This includes people with a family history of breast cancer or those who have had changes in the breast, called lesions, that could raise the risk of cancer. Research suggests that in these groups, certain aromatase inhibitors may help reduce breast cancer risk.

You and your healthcare team may decide to use aromatase inhibitors to help lower your risk of breast cancer. These medicines have not been approved by the U.S. Food and Drug Administration for this use, however.

More studies are being done to see if aromatase inhibitors can lower the risk of breast cancer in those with DNA changes that increase their breast cancer risk.