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Calcium channel blockers are medications used to lower blood pressure. They work by preventing calcium from entering the cells of the heart and arteries. Calcium causes the heart and arteries to squeeze (contract) more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open.

Some calcium channel blockers can also slow the heart rate, which can further lower blood pressure. The medications may also be prescribed to relieve chest pain (angina) and control an irregular heartbeat.

Calcium channel blockers are also called calcium antagonists.