Interactions

Possible interactions include:

• Antipsychotics. Use of DHEA with antipsychotics such as clozapine (Clozaril, Versacloz, others) might reduce the drug's effectiveness.
• Carbamazepine (Tegretol, Carbatrol, others). Use of DHEA with this drug used to treat seizures, nerve pain and bipolar disorder might reduce the drug's effectiveness.
• Estrogen. Don't use DHEA with estrogen. Combining DHEA and estrogen might cause symptoms of excess estrogen, such as nausea, headache and insomnia.
• Lithium. Use of DHEA with lithium might reduce the drug's effectiveness.
• Selective serotonin reuptake inhibitors. Use of DHEA with this type of antidepressant might cause manic symptoms.
• Testosterone. Don't use DHEA with testosterone. Combining DHEA and testosterone might cause symptoms such as low sperm count and enlarged breasts in men (gynecomastia) and the development of typically male characteristics in women.
• Triazolam (Halcion). Using DHEA with this sedative might increase the effects of this drug, causing excessive sedation and affecting your breathing and heart rate.
• Valproic acid. Use of DHEA with this medication used to treat seizures and bipolar disorder might reduce the drug's effectiveness.