Mayo Clinic Care Network Content
Articles

Kratom: Unsafe and ineffective

Research continues

Researchers continue to study the effects of kratom. Studies so far have found that kratom has many safety issues.

Kratom has been reported to react with other medicines. This may lead to severe effects, such as liver damage and death. More research is needed.

In a study testing kratom as a treatment for symptoms of quitting opioids, called withdrawal, people who took kratom for more than six months reported withdrawal symptoms like those from opioid use. And people who use kratom may begin craving it. They may need treatments given for opioid addiction, such as buprenorphine (Brixadi, Sublocade, others) and buprenorphine-naloxone (Suboxone, Zubsolv).

Kratom also affects babies during pregnancy. When a pregnant person uses kratom, the baby may be born with symptoms of withdrawal and need treatment.

Kratom products have been found to have heavy metals, such as lead, and harmful germs, such as salmonella, in them. Salmonella poisoning can be fatal. The FDA has linked more than 35 deaths to salmonella-tainted kratom.

Kratom is not regulated in the United States. But federal agencies are taking action to fight false claims about kratom. In the meantime, your safest choice is to work with your healthcare professional to find other treatments.