Selective serotonin reuptake inhibitors

Selective serotonin reuptake inhibitors (SSRIs) are medicines commonly used to treat depression and anxiety. They are considered the first line treatment for depression and anxiety after birth.

While SSRIs do enter breast milk, the amount can vary depending on the medicine. In general, studies have found that breastfeeding while taking these medicines is safe. Occasionally, mild side effects can happen in the infant including irritability or poor feeding. Untreated and undertreated mental health conditions are associated with poor outcomes for people who have given birth. In general, stopping effective medicines for mental health during the postpartum period increases the risk of relapse and is not recommended.

Sertraline and paroxetine may be preferable during breastfeeding due to lower amounts in breast milk.