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Aspirin-exacerbated respiratory disease (AERD), also called Samter's triad, has three features:

• Asthma, although only a small number of people with asthma will develop AERD.
• Nasal polyps that often come back, even after taken out by surgery.
• Problems with taking aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin IB, others) and naproxen. Keep in mind that aspirin or NSAIDs may be in cold medicines and other medicines.

Usually, warning signs of AERD don't show up until people have reached their 30s or 40s, but AERD can sometimes happen in children.