Treating xylazine use

If you suspect someone has overdosed on xylazine, call emergency medical services right away. While there is no treatment for xylazine itself, other treatments may be used. Because xylazine is often combined with an opioid, a medicine used to treat opioid overdose, called naloxone, may be used. Medicines used to treat low blood pressure and low heart rate also may be used to treat the symptoms of xylazine use and withdrawal.