Diseases and Conditions

Epithelioid sarcoma

Overview Diagnosis Treatment


Epithelioid sarcoma is a rare, slow-growing type of soft tissue cancer. Most cases begin in the soft tissue under the skin of a finger, hand, forearm, lower leg or foot, though it can start in other areas of the body.

Typically, epithelioid sarcoma starts as a small firm growth or lump that's painless. It usually starts out as a single growth, but multiple growths may occur by the time a person seeks medical help. Sometimes this sarcoma appears as ulcers that don't heal, looking like open wounds over the growths.

The classic form (distal-type) of epithelioid sarcoma mainly occurs in teenagers and young adults. A rarer form, called large-cell (proximal-type) epithelioid sarcoma, tends to be more aggressive and mainly affects adults.

Epithelioid sarcoma tends to have a high rate of recurrence and can spread to other areas. So if epithelioid sarcoma is suspected, it's best to seek care at a comprehensive cancer center that sees more cases of soft tissue sarcoma to ensure proper diagnosis and treatment, and to help prevent the cancer from recurring.