Diseases and Conditions
Essential thrombocythemia
Overview
Symptoms
Causes
Complications
Diagnosis
Treatment
Lifestyle and home remedies
Preparing for an appointment
Causes
Essential thrombocythemia is a type of chronic myeloproliferative disorder. That means your bone marrow, the spongy tissue inside your bones, makes too many of a certain type of cell. In the case of essential thrombocythemia, the bone marrow makes too many cells that create platelets.
It's not clear what causes this to happen. About 90% of people with the disorder have a gene mutation contributing to the disease.
If an underlying condition such as an infection or iron deficiency causes a high platelet count, it's called secondary thrombocytosis. Compared with essential thrombocythemia, secondary thrombocytosis causes less risk of blood clots and bleeding.