Treatment

MGUS doesn't require treatment. But your doctor is likely to recommend periodic checkups to monitor your health, probably starting six months after your diagnosis.

Watchful waiting

If you are at high risk of MGUS developing into a more serious condition, your doctor may recommend more frequent checkups so that any progression can be diagnosed and treatment started as soon as possible.

Your doctor is likely to watch for signs and symptoms such as:

• Bone pain
• Fatigue or weakness
• Unintentional weight loss
• Fever or night sweats
• Headache, dizziness, nerve pain, or changes in vision or hearing
• Bleeding
• Anemia or other blood abnormalities
• Swollen lymph nodes, liver or spleen

Medications

If you have osteoporosis, your doctor might recommend a medication to increase bone density. Examples include alendronate (Fosamax), risedronate (Actonel, Atelvia), ibandronate (Boniva) and zoledronic acid (Reclast, Zometa).