Symptoms

Symptoms of ovarian hyperstimulation syndrome often begin within a week after using injectable medications to stimulate ovulation, though sometimes it can take two weeks or longer for symptoms to appear. Symptoms can range from mild to severe and may worsen or improve over time.

Mild to moderate OHSS

With mild to moderate ovarian hyperstimulation syndrome, symptoms can include:

• Mild to moderate abdominal pain
• Abdominal bloating or increased waist size
• Nausea
• Vomiting
• Diarrhea
• Tenderness in the area of your ovaries

Some women who use injectable fertility drugs get a mild form of OHSS. This usually goes away after about a week. But, if pregnancy occurs, symptoms of OHSS may worsen and last several days to weeks.

Severe OHSS

With severe ovarian hyperstimulation syndrome, you might have:

• Rapid weight gain — more than 2.2 pounds (1 kilogram) in 24 hours
• Severe abdominal pain
• Severe, persistent nausea and vomiting
• Blood clots
• Decreased urination
• Shortness of breath
• Tight or enlarged abdomen

When to see a doctor

If you're having fertility treatments and you experience symptoms of ovarian hyperstimulation syndrome, tell your doctor. Even if you have a mild case of OHSS, your doctor will want to observe you for sudden weight gain or worsening symptoms.

Contact your doctor right away if you develop breathing problems or pain in your legs during your fertility treatment. This may indicate an urgent situation that needs prompt medical attention.