Diseases and Conditions

Pseudobulbar affect

Causes

Pseudobulbar affect (PBA) typically occurs in people with neurological conditions or injuries, including:

  • Stroke
  • Amyotrophic lateral sclerosis (ALS)
  • Multiple sclerosis (MS)
  • Traumatic brain injury
  • Alzheimer's disease
  • Parkinson's disease

While further research is needed, the cause of PBA is believed to involve injury to the neurological pathways that regulate the external expression of emotion (affect).